18th International Symposium on Dendritic Cells

11–14 October 2026 · Kona Kai Resort, San Diego · All times in Pacific Standard Time (PST)

This program is subject to change. Please check back for updates.

Sunday, 11 October

Opening day · Registration, Inaugural Keynote & Plenary 1

📋 1:00 PM – 7:00 PM Registration Open📍 Main Foyer

🎤 3:00 PM – 3:30 PM Welcome RemarksChair: Juliana Idoyaga📍 Point Loma 1 & 2

3:30 PM – 4:30 PM

Inaugural Keynote Speaker

Chair: Juliana Idoyaga

Keynote

📍 Point Loma 1 & 2

1 talk

3:30 PM

Chromatin-mediated control of dendritic cell function

Boris Reizis

Keynote · 60 min

☕ 4:30 PM – 5:00 PM Coffee/Tea Break & Networking📍 Point Loma 3

5:00 PM – 6:45 PM

Plenary 1: DC Development, Lineage Specification & Transcriptional Control

Chairs: Barbara Schraml & Shalin Naik

Plenary

📍 Point Loma 1 & 2

5 talks

5:00 PM

Mechanism of WDFY4-dependent cross-presentation in cDC1

Kenneth Murphy

Invited Speaker

5:25 PM

Blurring the Line: A Hybrid Mononuclear Phagocyte Population Across Tissues

Florent Ginhoux

Invited Speaker

5:50 PM

The transcription factor regulating tumor-associated macrophages in pancreatic cancer

Tomohiko Tamura

Invited Speaker

6:15 PM

Promoter-dependent IRF8 induction governs subset-specific cDC2 reprogramming during infection with intracellular pathogens

Daisuke Kurotaki

Short Talk

6:30 PM

Infection-specific regulation of cDC2poiesis shapes dendritic cell subset responses

Kyle T. Cunningham

Short Talk

🥂 6:45 PM – 8:15 PM Welcome Reception📍 Cabo Garden & Courtyard

Monday, 12 October

Plenary 2 & 3 · Parallel Symposia A & B · Ralph Steinman Legacy Symposium

📋 7:00 AM – 7:00 PM Registration Open📍 Main Foyer

8:00 AM – 9:45 AM

Plenary 2: DC Functional Heterogeneity: Subsets, Identity & Function

Chairs: Anne Krug & Boris Reizis

Plenary

📍 Point Loma 1 & 2

7 talks

8:00 AM

Surveillance of intestinal antigens by functionally diverse antigen-presenting cells

Dan Littman

Invited Speaker

8:25 AM

Thetis cells: Defining the Ontogeny and Function of a Novel APC Lineage

Chrysothemis Brown

Invited Speaker

8:50 AM

Rethinking Immaturity: Signals Shaping Dendritic Cell Function in Early Life

Barbara Schraml

Invited Speaker

9:15 AM

Transitional dendritic cells in innate and adaptive immunity

Raul Maqueda Alfaro

Short Talk

9:30 AM

Epigenetic Heterogeneity in Dendritic Cell Subsets Underlies Immune Response Variation

Mya Gough

Flash Talk

9:35 AM

Thymic myeloid cell heterogeneity reveals a novel population of perivascular transitional dendritic cells with antigen sampling capacity

Matous Voboril

Flash Talk

9:40 AM

Defining the factors governing intratumoral cDC1-CD8 T cell clusters

Maria Parra Reyes

Flash Talk

☕ 9:45 AM – 10:30 AM Coffee/Tea Break & Networking📍 Point Loma 3

10:30 AM – 12:15 PM

Plenary 3: Tissue Surveillance, Migration & Immune Coordination

Chairs: William Agace & Santiago Zelenay

Plenary

📍 Point Loma 1 & 2

7 talks

10:30 AM

Pathways of homeostatic dendritic cell maturation

Sophie Janssens

Invited Speaker

10:55 AM

Environment Patrolling by colonic Dendritic Cells

Ana-Maria Lennon-Dumenil

Invited Speaker

11:20 AM

Dendritic cells as architects of lymphoid tissue immunity

Michael Gerner

Invited Speaker

11:45 AM

Neuronal control of dendritic cell migration drives sex-biased skin immunity

Konrad Knöpper

Short Talk

12:00 PM

Influence of cancer cell mechanical properties on dendritic cell sentinel function

Yazmina Quintana Perez

Flash Talk

12:05 PM

Macrophage nibbling without killing: a novel endosomal route for CD8 T cell priming

Amy C Fan

Flash Talk

12:10 PM

Chemokine-Driven Spatial Niches Regulate Distinct APC-T cell Neighbourhoods within the Human Lymph Node

Marcus Ooi

Flash Talk

🍽️ 12:15 PM – 2:30 PM Lunch📍 Point Loma 3

12:30 PM – 2:30 PM

Poster Session 1

Poster

📍 Point Loma 3

68 posters

#100

Homologous MHC class I/II epitopes program cDC1-like differentiation of monocyte-derived dendritic cells via mTORC1 signaling inhibition

Sharon Bright Amanya

Poster

#101

Single-nucleus multiomic profiling of human dendritic cells heterogeneity

Simone Balin

Poster

#102

Pre-Defined Interferon Programs in Hematopoietic Stem Cells Shape Vaccine Responsiveness in Humans

Diego Diaz-Dinamarca

Poster

#103

Inflammatory signals during viral infection and sepsis impact dendritic cell development

Regine J. Dress

Poster

#104

Transcriptional insights into dendritic cell survival

Signe Holst

Poster

#105

Trim33 is essential for the development and maintenance of plasmacytoid and type 1 conventional dendritic cells

Pei-Feng Hsu

Poster

#106

Deubiquitinase USP22 is Required for Conventional Dendritic Cell 1 (cDC1) Development

Chieh-Yu (Jessie) Lee

Poster

#107

Dual role of Mef2c in promoting pDC development and limiting antiviral responses

Tai-Ling Li

Poster

#108

RORγt+ Dendritic Cells are a distinct lymphoid-derived lineage

Patrick Fernandes Rodrigues

Poster

#109

Clarifying Dendritic cell terminology in the context of single-cell diversity

Sunrito Mitra

Poster

#110

CD16/32b surface expression reflects dendritic cell activation, rather than a stable dendritic cell subset.

Sunrito Mitra

Poster

#111

Distinct dendritic cell subsets drive sequential T cell priming phases

Enrico Dotta

Poster

#112

GM-CSF and specific type 2 cytokines induce CD103+ and CD301b+ cell states in cDC1s and cDC2s

Diana Dudziak

Poster

#113

Epigenetic Heterogeneity in Dendritic Cell Subsets Underlies Immune Response Variation

Mya Gough

Poster

#114

Temporal analysis of the transcriptional regulation of dendritic cell activation reveals subtype-specific gene regulatory networks and key transcription factors

Ignacio Heras-Murillo

Poster

#115

Decoding the functional heterogeneity of RORγt+ dendritic cells

Pin-Yu Kuo

Poster

#117

Revisiting antigen presenting cell lineages in intestinal immunity

Gianfranco L Yee

Poster

#118

Age- and tissue-dependent diversity of human plasmacytoid dendritic cells uncovers a cycling subset dominant in early life and cancer

Alina Ulezko Antonova

Poster

#119

Temporal Dynamics of MxA, ISG15, and CCL5 Expression in Monocyte-Derived Alpha-Type 1 Polarized Dendritic Cells

Guilherme Castellani

Poster

#120

Deletion of Phosphoinositide 3-kinase-γ (PI3Kγ) enhances conventional Dendritic Cell Cross-Presentation of Immune Complexes

Kenneth M Adusei

Poster

#121

Comparative analysis of antigen presentation by APC subsets using a mouse model expressing multiple disease-relevant antigens

Camillo Bechi Genzano

Poster

#122

Efferocytosis and necrophagy are distinct pathways for dead cell uptake and presentation by cDC1s

Victor Bosteels

Poster

#124

Unravelling the processing pathway for transmembrane proteins in human dendritic cells

Tongxiang Chen

Poster

#125

Macrophage nibbling without killing: a novel endosomal route for CD8 T cell priming

Amy C Fan

Poster

#126

A point mutation in Interferon Regulatory Factor 4 impairs dendritic cell instruction of T cell fate

Yanran Fan

Poster

#130

Migratory dendritic cells mediate communication between the central nervous system and the peripheral immune system

Viola Bugada

Poster

#131

Impact of skin fibrosis on dendritic cell function and migration

Vincent Calmettes

Poster

#132

BHLHE40/DEC1 programs epidermal Langerhans Cell identity

Sally Connolly

Poster

#133

Respiratory virus induced changes in pulmonary conventional dendritic cell subsets.

Maddisen Dwelley

Poster

#134

Langerhans cells fine-tune axonal guidance of nociceptor neurons in health and disease

Yonatan Ganor

Poster

#135

Bone morphogenetic protein signaling promotes tolerogenic DC differentiation in psoriatic inflammatory lesions and histiocytosis

Sara Gvozden Popovic

Poster

#136

Transitional dendritic cells give rise to skin CD11b⁻ DC2s

Hai Ni

Poster

#137

Developmentally related plasmacytoid and transitional dendritic cells occupy distinct niches in the mouse spleen

Selma Cifric

Poster

#138

Interplay between dendritic cells and macrophages drives generation of commensal-specific homeostatic intestinal Th17 cells

Junjie Ma

Poster

#139

Mature dendritic cells orchestrate age-associated regulatory lymphoid niches in tissues

Ines Marin

Poster

#140

Dendritic cells, bridging neuromodulation and immunity

MARIA MML MARTINEZ-LOPEZ

Poster

#141

Transcription factor Etv3 controls the positioning of mature dendritic cells within the lymph node

Daniel C Martinez-Krams

Poster

#142

Maternal Antibodies Regulate the Establishment of Oral and Salivary Mucosal Immunity

Reem Naamneh

Poster

#143

Cytoskeletal control of podosome–focal adhesion dynamics in GM-CSF-derived dendritic cells

Adrianna Niedzielska

Poster

#144

Chemokine-Driven Spatial Niches Regulate Distinct APC-T cell Neighbourhoods within the Human Lymph Node

Marcus Ooi

Poster

#145

STAT1 signalling shapes the function of type 2 conventional dendritic cells in lungs of weanling mice

Kaushikk Ravi Rengarajan

Poster

#146

Defining the role of human anogenital antigen-presenting cells in HIV transmission

Jake W Rhodes

Poster

#147

Fantastic antigen-presenting cells and where to find them: Microglia-CD8+ T cell duos in the aged Alzheimer's brain following peripheral infections

Michael A. LaPorta

Poster

#148

Yogesh Sardana

Poster

#149

Thymic myeloid cell heterogeneity reveals a novel population of perivascular transitional dendritic cells with antigen sampling capacity

Matous Voboril

Poster

#150

Dissecting subset-specific activation programmes of skin migratory type 2 dendritic cells

Olivier Lamiable

Poster

#151

Characterization of type-2 dendritic cell populations in skin

Olivier Lamiable

Poster

#152

Discovery of interactions underlying activated cDC niches in tumors

Lomax Pass

Poster

#153

Harnessing the XCL1-XCR1 chemokine-dendritic cell axis for cancer immunotherapy

Ning Kuo

Poster

#154

cDC1 emerge as a dominant response-associated feature within multicellular immune niches in melanoma and lung cancer

Saraí G De León Rodríguez

Poster

#160

Phosphoglycerate dehydrogenase moonlights to shape dendritic cell crosstalk and effector functions

Ebenezer Asiedu

Poster

#161

Threonine is critical for dendritic cell development and effector functions

Ebenezer Asiedu

Poster

#162

Calcium dynamics in Dendritic cells in response to bacteria

Gaetan Barbet

Poster

#163

AMPK is a metabolic checkpoint for cDC1 identity and function

Pedro P. Cunha

Poster

#166

Short-term high-fat diet feeding disrupts cDC1 homeostasis via reduced lymphocyte-derived FLT3L and induces expansion of Th17 T-cells

Paul Maier

Poster

#167

The solute carrier transporter SLC15A4 promotes anti-viral signaling in dendritic cells

Adriana R Mantegazza

Poster

#168

Dying cell-derived polyamines modulate dendritic cell phagocytosis and adaptive priming

Chang Y Moon

Poster

#169

Aryl Hydrocarbon Receptor Inhibition Activates Mito-calcium/mtROS/IL-12 Axis in Dendritic Cells to Promote Tumor Suppression

Mridula Prakash Menon

Poster

#170

Role of antigen presenting cells in the changes in immune response to SARS-Cov-2 with advancing age in humans

Anshu AGRAWAL

Poster

#174

Plasmacytoid dendritic cells initiate local type I interferon responses via contact-dependent recognition of infected macrophages

Annesa Das

Poster

#175

Pro-Inflammatory Response of Human Monocyte-Derived Dendritic Cells to Bacterial Biofilms

Stefania Gallucci

Poster

#176

Single-Cell Characterization of Dendritic Cell Progenitor Adaptations During a Viral Infection

Hector U Gaspar-Eslava

Poster

#178

RIG-I-like receptor-dependent type I Interferon regulates antigen dose and activation in yellow fever vaccine 17D-infected antigen presenting cells

Anne Krug

Poster

#179

Transcriptional profiling reveals subset-specific cathepsin responses in cDC1 and cDC2 during ectromelia virus infection

Adrianna Niedzielska

Poster

#182

Functional heterogeneity of splenic DC2 subsets during acute LCMV infection driven by subset identity

Anne B. Krug

Poster

#184

Type III IFNs production in type I classical dendritic cells to virus-infected cells

TAEJIN YUN

Poster

#185

Deciphering the mechanisms underlying human plasmacytoid dendritic cell function and exhaustion

Dina Zangwill

Poster

#186

SAPS3 Regulates T Cell Exhaustion and Antiviral Immunity during Chronic Viral Infection

Xiyu Chen

Poster

2:30 PM – 4:00 PM

Parallel Symposium A: DC Biology, Technologies & Therapeutic Opportunities

Chairs: Filipe Pereira & Diana Dudziak

Parallel A

📍 Point Loma 1 & 2

2:30 PM

The role of plasmacytoid dendritic cells in anti-viral immunity and in homeostasis

Elena Tomasello

Invited Speaker

2:55 PM

Tim-3–Targeted Vaccines Overcome Tumor Immunosuppression and Reduce cDC1 Dependence to Elicit Potent Anti-Tumor Immunity

Aimin Jiang

Short Talk

3:10 PM

Dissecting hierarchical dendritic cell–T cell interactions in tumour immunity using in vivo enzymatic labelling

Aleksey Chudnovskiy

Short Talk

3:25 PM

Fine-Tuned Help: Orchestrating Dendritic Cell-T Cell Crosstalk in Antitumor Immunity

Eynav Klechevsky

Short Talk

3:40 PM

Virus-like particles enable targeted gene engineering and pooled CRISPR screening in primary human myeloid cells

Julia Carnevale

Flash Talk

3:45 PM

Revisiting Dendritic Cells in Autoimmunity

Juan Villar Vesga

Flash Talk

3:50 PM

Large Scale Production of Human Conventional Type I Dendritic Cells for Cancer Immunotherapy

Sreekumar Balan

Flash Talk

2:30 PM – 4:00 PM

Parallel Symposium B: DC Metabolism & Cellular Programming of Function & Fate

Chairs: Connie Krawczyk & Gaetan Barbet

Parallel B

📍 Coronado Room

2:30 PM

Connecting DC metabolism and function

David Sancho

Invited Speaker

2:55 PM

Conventional dendritic cells exhibit tissue-specific characteristics that are regulated by mitochondrial metabolism

Stefanie K Wculek

Short Talk

3:10 PM

O-GlcNAcylation regulates dendritic cell transcriptional stability

Jose A Villadangos

Short Talk

3:25 PM

IL-21 as a central driver of immunosenescence: linking pulmonary dysfunction and neurodegeneration

Anshu Agrawal

Short Talk

3:40 PM

Dying cell-derived polyamines modulate dendritic cell phagocytosis and adaptive priming

Chang Y Moon

Flash Talk

3:45 PM

The solute carrier transporter SLC15A4 promotes anti-viral signaling in dendritic cells

Adriana R Mantegazza

Flash Talk

3:50 PM

Aryl Hydrocarbon Receptor Inhibition Activates Mito-calcium/mtROS/IL-12 Axis in Dendritic Cells to Promote Tumor Suppression

Mridula Prakash Menon

Flash Talk

☕ 4:00 PM – 4:45 PM Coffee/Tea Break & Networking📍 Point Loma 3

4:45 PM – 6:45 PM

Ralph Steinman Legacy Symposium: Foundational Discoveries that Shaped the Field

Chairs: Juliana Idoyaga & Bei Wang

Legacy Symposium

📍 Point Loma 1 & 2

4 talks + discussion

4:45 PM

The early days of dendritic cells

Jacques Banchereau

Invited Speaker

5:05 PM

Dendritic cells rule the cancer immunity cycle

Ira Mellman

Invited Speaker

5:25 PM

Ralph Steinman's legacy in dendritic cell targeting and the balance between tolerance and protective immunity

Laura Bonifaz

Invited Speaker

5:45 PM

Transcription factor Etv3 controls the tolerogenic function of dendritic cells

Nicholas M Adams

Early Career Investigator Award Talk

6:10 PM

Reflections by Bei Wang, Diana Dudziak, Björn Clausen, Juliana Idoyaga & Shin-ichiro Fujii

Juliana Idoyaga

Discussion

🍽️ 7:00 PM – 11:00 PM Dinner on Your Own

Tuesday, 13 October

Plenary 5 · Parallel Symposia C & D · Plenary 4 · Conference Dinner

📋 7:00 AM – 5:30 PM Registration Open📍 Main Foyer

☕ 9:45 AM – 10:30 AM Coffee/Tea Break & Networking📍 Point Loma 3

11:00 AM – 12:45 PM

Plenary 5: DCs in Mucosal Immunity, Homeostasis & Host Defense

Chairs: Andrew Harman & Yonatan Ganor

Plenary

📍 Point Loma 1 & 2

7 talks

11:00 AM

Unravelling Dendritic cell-CD4+ T cell crosstalk in the inflamed mucosa of Crohn’s disease patients

William Agace

Invited Speaker

11:25 AM

Distinct antigen-presenting cells instruct divergent microbiota-specific T cell fates in the intestinal immune system

Daniel Mucida

Invited Speaker

11:50 AM

A subset of DC specialized in tolerance induction

Marco Colonna

Invited Speaker

12:15 PM

Dysbiosis-induced expansion of AXL-positive inflammatory type 3 dendritic cells triggers pre-clinical autoimmunity

Roxane Tussiwand

Short Talk

12:30 PM

STAT1 signalling shapes the function of type 2 conventional dendritic cells in lungs of weanling mice

Kaushikk Ravi Rengarajan

Flash Talk

12:35 PM

RORγt+ Dendritic Cells are a distinct lymphoid-derived lineage

Patrick Fernandes Rodrigues

Flash Talk

12:40 PM

GM-CSF and specific type 2 cytokines induce CD103+ and CD301b+ cell states in cDC1s and cDC2s

Diana Dudziak

Flash Talk

🍽️ 12:45 PM – 2:00 PM Lunch📍 Point Loma 3

12:45 PM – 2:00 PM

Poster Session 2

Poster

📍 Point Loma 3

67 posters

#200

G-baToN: in vivo Cell-Cell Interaction Labeling Technology

Christie Chang

Poster

#201

Virus-like particles enable targeted gene engineering and pooled CRISPR screening in primary human myeloid cells

Carter Ching

Poster

#202

Assessment of silica nanoparticles internalization by alpha-type-1 polarized dendritic cells (αDC1)

Silvia de Jesus Mota

Poster

#203

Virus-like particles enable targeted gene engineering and pooled CRISPR screening in primary human myeloid cells

Jack Reid

Poster

#204

Production of dendritic cells from arrested myeloid progenitors at scale

Erron Titus

Poster

#205

Unveiling genes in dendritic cells that enhance T cell priming through functional single cell-cell interaction analysis

Camilla Valente

Poster

#210

Inducing regulatory dendritic cells with cellular reprogramming

Abigail R Altman

Poster

#211

FOOD AVERSION IN THE CONTEXT OF PEANUT ALLERGY

Marcos Felipe Andrade de Oliveira

Poster

#212

Tolerogenic dendritic cell-derived extracellular vesicles prime CD8 T Cells toward impaired immune synapse formation and reduced cytotoxic capacity

Daniel DB Beckers

Poster

#213

A critical role for RORgt+ DCs in viral-mediated loss of oral tolerance

Edith E Campana

Poster

#214

Single-cell multi-omics of human dendritic cell differentiation reveals subtype-specific disease risk mechanisms

Ofir Cohn

Poster

#215

Single-cell spatial transcriptomics of fixed, paraffin-embedded biopsies links dendritic cell-enriched gut-associated lymphoid aggregates to an archetype of vedolizumab non-response

Alexis J Combes

Poster

#216

Dissecting the development and function of PRDM16+ tolerogenic dendritic cells

Liuhui Fu

Poster

#217

Characterizing dendritic cells in APECED using an induced pluripotent stem cell model and multiplex tissue imaging

Eira Karvonen

Poster

#218

Transcriptional regulation of OX40L expression during dendritic cell maturation

Timothy Kung

Poster

#219

Dysregulated dendritic cell landscape in pre-systemic sclerosis across autoantibody subtypes

Heena Mehta

Poster

#220

Modulating innate signaling in skin antigen presenting cells using microneedles to promote antigen-specific tolerance in autoimmunity

Valinteshley D. Pierre

Poster

#221

Spatially organised IFNγ-instructed dendritic cell niches sustain human chronic inflammation

Andreas Schlitzer

Poster

#223

Revisiting Dendritic Cells in Autoimmunity

Juan Villar Vesga

Poster

#224

Oxidized mitochondrial DNA drives pDC-dependent Tfh differentiation in autoimmunity

Hongxu Xian

Poster

#225

Erythropoietin receptor on cDC1s dictates immune tolerance

Xiangyue Zhang

Poster

#226

IFN-I–driven Ly6Chi myeloid cell expansion and anti-SSA/Ro autoimmunity are associated with myocardial injury in lupus

Haiting Wang

Poster

#230

Regulation of anti-cancer immunity by a natural killer cell – dendritic cell innate immune axis

Kevin C Barry

Poster

#231

Malignant cell-intrinsic Snai2 directs monocyte infiltration and differentiation in the tumor microenvironment

Molly Bassette

Poster

#232

Evaluating glioblastoma dendritic cell surveillance in aged hosts

Sarah L Cook

Poster

#233

Restraining intratumoral lymphangiogenesis improves dendritic cell maturation in the melanoma-draining lymph node

Naomi Besson

Poster

#234

Victory with Consequences: CTLA-4 ablation in Dendritic Cells defeats tumors but destroys Tolerance

Nalini Bisht

Poster

#235

Dissecting the origins, destinations, and roles of migratory dendritic cells in cancer

Alexandra Bowman

Poster

#236

Tumor Cell-Intrinsic IL-1 Signaling Inhibits cDC1s to Drive Systemic Immune Dysfunction

Timothy F Campbell

Poster

#237

Investigating how dendritic cells coordinate anti-tumor immunity in PDAC and neuroblastoma

Kate Carbone

Poster

#238

Mapping the CLCF1 Signaling Axis to Regulatory Dendritic Cells in KRAS-Mutant Lung Cancer

Sarah A Castro

Poster

#240

Tumor‑Derived Chemokine Shapes cDC1 Function and Trafficking to Tumor‑Draining Lymph Nodes

PIYUSH CHAUDHARY

Poster

#241

Type 2 conventional dendritic cells limit responsiveness to cancer immunotherapy

Nayvin W Chew

Poster

#243

Tumor dsRNA sensing drives antigen-specific T cell immunity via DC-dependent and independent priming

Therese Cordero Dumit

Poster

#244

Intrathymic dendritic cells contribute to immune dysregulation in thymic epithelial tumors

Silvia Della Bella

Poster

#245

Radiotherapy promotes the recruitment and activation of intra-tumoural DCs and enhances CD64+CCR7+ cDC2 egress to the draining lymph node

Christopher Jones

Poster

#246

Multi-compartment profiling identifies mature regulatory dendritic cells as a conserved immune state associated with effective anti-tumour immunity in early breast cancer

Hiu-Yan Lau

Poster

#247

Reprogramming suppression: CD40-activated dendritic cells drive Treg-to-effector conversion

Vivien I Maltez

Poster

#248

Intratumor mature DCs enriched in immunoregulatory molecules support local CD4+ Foxp3+ regulatory T cell activation

Claire Murat

Poster

#249

Distinct stimulatory signals promote the diversification of cDC1 functional states in tumors

Nadine Nuschele

Poster

#250

Defining the factors governing intratumoral cDC1-CD8 T cell clusters

Maria Parra Reyes

Poster

#252

Influence of cancer cell mechanical properties on dendritic cell sentinel function

Yazmina Quintana Perez

Poster

#253

Tumor cells dying of ferroptosis limit cDC1-mediated anti-cancer immunity

Lukas Ramsauer

Poster

#254

Dissecting the contributions of dendritic cell lineage and activation state to T cell responses in cancer

Erin Richardson

Poster

#255

Self-antigen disrupts cDC1 mediated antitumor responses

Megan K Ruhland

Poster

#256

HPK1-deficient dendritic cells overcome checkpoint resistance by organizing IFNγ- dependent immune niches in cold pancreatic tumors

Wanjing Shang

Poster

#257

cDC1 engagement induces Th1 differentiation and tumor regression in vivo.

Seonhui Shim

Poster

#258

Interferon-stimulated dendritic cells in the tumor microenvironment regulate immunotherapy response

Jason Shoush

Poster

#259

Polarization-dependent control of dendritic cell CTLA-4 transcription by a GATA3–C/EBP-β rheostat

Jonathan Vazquez-Perez

Poster

#260

CXCL9+ cDC1 define an early immune surveillance state in preneoplastic breast cancer

Aurélien Voissiere

Poster

#261

PSGL-1 expression on myeloid cells inhibits anti-tumor immunity and promotes melanoma tumor growth

Jamie-Jean De La Torre

Poster

#270

Large Scale Production of Human Conventional Type I Dendritic Cells for Cancer Immunotherapy

Sreekumar Balan

Poster

#271

Tetanus toxoid preconditioning enhances dendritic cell vaccine migration and patient survival in glioblastoma clinical trials: experience with ATTAC and the validation ELEVATE study

Kristen Batich Vaios

Poster

#272

Ongoing Survival Analysis of DOC1021 for Treatment of Resectable or Borderline Resectable Pancreatic Ductal Adenocarcinoma

William K Decker

Poster

#273

Inflammatory Conditions Determine DC Ability to Present Antigenic Epitopes from Cancer Cells and Generate Multi-Epitope‑Specific T Cells

Bowen Dong

Poster

#274

Polarized Dendritic Cells Are Efficient Ex Vivo Inducers of Multi-Epitope‑Specific T Cells for Adoptive Cancer Therapy

Bowen Dong

Poster

#275

Regulating myeloid cells to promote mature tertiary lymphoid structures and enhance anti-tumor immunity

Elizabeth E Evans

Poster

#276

Development and optimization of dendritic cell vaccines for breast cancer treatment

Pierrick GJ Fournier

Poster

#277

Immune Remodeling mRNA Drives Durable Anti-Tumor Immunity

Christopher Garris

Poster

#278

Evaluation of the anesthetics Sevoflurane’s and Propofol’s effects on the phenotype and function of monocyte-derived dendritic cells

Bárbara P Gustineli

Poster

#279

Solving the manufacturing bottleneck of GMP-grade DC1 for solid cancer immunotherapy.

Devi Jenika

Poster

#280

Short-Term-Activated cDC1s Synergize with PD-1 Blockade, Inducing Effector CTL Differentiation, Tumor Rejection and Immune Memory

Pawel Kalinski

Poster

#282

Autologous Dendritic Cells and Autologous Tumor Microfragments Reveal Specific Reactivity in 95% of Tumors

Michael T Lotze

Poster

#283

Mechanistic Investigation of Plinabulin in Combination with Datopotamab Deruxtecan, a TROP2-directed Antibody-Drug Conjugate Carrying a Topoisomerase 1 Inhibitor, Without or With Pembrolizumab

June Lu

Poster

#287

CAR-DC1: A novel next-generation dendritic cell therapy for targeting solid tumours

Devi Jenika

Poster

#288

Virus-like particles enable targeted gene engineering and pooled CRISPR screening in primary human myeloid cells

Julia Carnevale

Poster

#289

A single-cell atlas of dendritic cell remodeling across the human lifespan, vaccination, viral infection and SLE

Djamel Nehar Belaid

Poster

2:00 PM – 3:30 PM

Parallel Symposium C: DCs in Infection & Immunity

Chairs: Michael Constantinides & Adriana Mantegazza

Parallel C

📍 Point Loma 1 & 2

2:00 PM

Cellular Stress Meets Immunity: IRE1-Dependent Programming of Dendritic Cell Function

Fabiola Osorio

Invited Speaker

2:25 PM

Plasmacytoid dendritic cell adaptations upon viral infection: heterogeneity, functional loss and fate conversion

Carolina Chiale

Short Talk

2:40 PM

Dendritic Cell Diversity During Blood Stage of Murine Malaria

Fernando B Sulczewski

Short Talk

2:55 PM

Defining the role of human anogenital antigen-presenting cells in HIV transmission

Andrew N Harman

Short Talk

3:10 PM

Inflammatory signals during viral infection and sepsis impact dendritic cell development

Regine J. Dress

Flash Talk

3:15 PM

Deciphering the mechanisms underlying human plasmacytoid dendritic cell function and exhaustion

Dina Zangwill

Flash Talk

3:20 PM

Functional heterogeneity of splenic DC2 subsets during acute LCMV infection driven by subset identity

Anne B. Krug

Flash Talk

2:00 PM – 3:30 PM

Parallel Symposium D: DCs in Tolerance, Allergy, Autoimmunity & Chronic Inflammation

Chairs: Nicholas Adams & Roxane Tussiwand

Parallel D

📍 Coronado Room

2:00 PM

Signaling through erythropoietin receptors on cDC1s promotes immune tolerance

Edgar Engleman

Invited Speaker

2:25 PM

Pleiotropic IL-10 can drive opposite effects in dendritic cells following MHC-II restricted, antigen-specific tolerogenic immunotherapy

Rebecca Leylek

Short Talk

2:40 PM

SIRPα regulates homeostatic maturation of Notch2-dependent cDC2 and development of autoimmunity

Yasuyuki Saito

Short Talk

2:55 PM

Dissecting IL-10 signaling in myeloid antigen-presenting cells during colorectal tumor development

Björn E. Clausen

Short Talk

3:10 PM

Oxidized mitochondrial DNA drives pDC-dependent Tfh differentiation in autoimmunity

Hongxu Xian

Flash Talk

3:15 PM

Single-cell spatial transcriptomics of fixed, paraffin-embedded biopsies links dendritic cell-enriched gut-associated lymphoid aggregates to an archetype of vedolizumab non-response

Alexis J Combes

Flash Talk

3:20 PM

Reprogramming suppression: CD40-activated dendritic cells drive Treg-to-effector conversion

Vivien I Maltez

Flash Talk

☕ 3:30 PM – 4:15 PM Coffee/Tea Break & Networking📍 Point Loma 3

4:15 PM – 5:15 PM

Plenary 4: DCs in Skin Immunity: Function, Communication & Adaptation

Chairs: Eynav Klechevsky & Björn Clausen

Plenary

📍 Point Loma 1 & 2

5 talks

4:15 PM

How tissues sustain resident T cell immunity

Laura Mackay

Invited Speaker

4:40 PM

Sequential priming by distinct dendritic cell subsets shapes effector CD4 T cell fate

Yosuke Kumamoto

Short Talk

4:55 PM

Distinct dendritic cell subsets drive sequential T cell priming phases

Enrico Dotta

Flash Talk

5:00 PM

Langerhans cells fine-tune axonal guidance of nociceptor neurons in health and disease

Yonatan Ganor

Flash Talk

5:05 PM

Characterization of type-2 dendritic cell populations in skin

Olivier Lamiable

Flash Talk

🌅 5:15 PM – 7:00 PM Free Afternoon

🎉 7:00 PM – 11:00 PM End of Conference Networking Dinner

Wednesday, 14 October

Keynote Address · Translational Roundtable · Plenary 6 · Therapies Symposium · Trainee Session · Awards & Closing Ceremony

📋 7:00 AM – 4:00 PM Registration Open📍 Main Foyer

8:00 AM – 9:00 AM

Keynote Address

Chair: Juliana Idoyaga

Keynote

📍 Point Loma 1 & 2

1 talk

8:00 AM

The exceptionalism of the cDC1 lineage and its central role in tumor immunity

Miriam Merad

Keynote · 60 min

9:00 AM – 10:00 AM

Translational Roundtable: From DC Biology to Therapeutics

Chair: Ira Mellman

Roundtable

📍 Point Loma 1 & 2

9:00 AM

Panel discussion: Bridging fundamental dendritic cell biology to clinical therapeutic application

Edgar Engleman, Miriam Merad & Filipe Pereira

Invited Session

☕ 10:00 AM – 10:45 AM Coffee/Tea Break & Networking📍 Point Loma 3

10:45 AM – 12:35 PM

Plenary 6: DCs in Cancer Immunity & Therapy

Chairs: Jose Villadangos & Kelly Kersten

Plenary

📍 Point Loma 1 & 2

8 talks

10:45 AM

CCR7+ activated dendritic cells: defining the state that drives cancer immunity

Santiago Zelenay

Invited Speaker

11:10 AM

On the Nature of Antigen Uptake and Presentation in the TME

Max Krummel

Invited Speaker

11:35 AM

The tumor-sentinel lymph node immuno-migratome reveals CCR7⁺ dendritic cells drive response to sequenced immunoradiotherapy

Robert Saddawi-Konefka

Short Talk

11:50 AM

Context-Dependent DC2 States in Human Cancer

Kristen Radford

Short Talk

12:05 PM

Dendritic-Cell Spatial Organization Shapes Tissue Immunity

Christine Moussion

Short Talk

12:20 PM

Regulation of anti-cancer immunity by a natural killer cell – dendritic cell innate immune axis

Kevin C Barry

Flash Talk

12:25 PM

CAR-DC1: A novel next-generation dendritic cell therapy for targeting solid tumours

Devi Jenika

Flash Talk

12:30 PM

Ongoing Survival Analysis of DOC1021 for Treatment of Resectable or Borderline Resectable Pancreatic Ductal Adenocarcinoma

William K Decker

Flash Talk

🍽️ 12:35 PM – 2:30 PM Lunch📍 Point Loma 3

🎓 1:00 PM – 2:00 PM Trainee Session (Meet the Editor)📍 Point Loma 1 & 2

Claire Olingy – Senior Editor, Science Immunology

Michael Lotze – Editor in Chief, Journal for Immunotherapy of Cancer

Montserrat (Montse) Col Vidal – Senior Scientific Editor, Journal of Experimental Medicine (JEM)

2:30 PM – 4:15 PM

Translating DC Biology into Therapies Symposium

Chairs: Max Krummel & I. Jolanda M. de Vries

Symposium

📍 Point Loma 1 & 2

6 talks

2:30 PM

Next-gen DC1 immunotherapy: Making the theoretical possible

Shalin Naik

Invited Speaker

2:55 PM

Inducing lymphoid niches across cancers by tumor-to-dendritic cell reprogramming

Filipe Pereira

Invited Speaker

3:20 PM

Using mRNA-LNP technology to manipulate conventional dendritic cell biology

Justine Mintern

Short Talk

3:35 PM

Spatiotemporal Coordination of NK Cells and CTLs Drives Remodeling of Poorly T Cell–Infiltrated Tumor Microenvironments

Shin-ichiro Fujii

Short Talk

3:50 PM

CD28 Costimulatory Bispecifics Synergize with Chemotherapy and ADCs to Broaden Antitumor T Cell Immunity

Bei Wang

Short Talk

4:05 PM

Regulating myeloid cells to promote mature tertiary lymphoid structures and enhance anti-tumor immunity

Elizabeth E Evans

Flash Talk

🏆 4:15 PM – 5:00 PM Awards & Closing Ceremony📍 Point Loma 1 & 2

DC2026 PROGRAM

18th International Symposium on Dendritic Cells

Sunday, 11 October

Monday, 12 October

Tuesday, 13 October

Wednesday, 14 October